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Monolaurin and Gastritis

Last Updated: January 8, 2019 | First Published: August 20, 2018
Reviewed by: Dr. Jennifer Meza, M.D.

Treating Stomach Ulcers (caused by H. Pylori) with Monolaurin

The number of ulcer-related cases presented in hospitals is between 500k and 900k per year.

The number of ulcer-related cases presented in hospitals is between 500k and 900k per year.

An ulcer is a sore area or a hole in the lining of the stomach. Ulcers of the stomach and the small intestine are mostly caused by a spiral-shaped bacteria called Helicobacter pylori (H. Pylori), and they can affect people from any age group (Ref #1). Gastritis is a disease that causes ulcers in the stomach through inflammation in the inner lining of the stomach. It can be caused by various factors including excessive consumption of alcohol or a normal dose of some medications like anti-inflammatory drugs.

Symptoms of Gastritis

The most common symptom is the pain in the upper abdomen area. When the lining of the stomach becomes inflamed, a burning sensation can be felt in this area of the body as it is in direct contact with the stomach. Patients may experience this pain in the early hours of the morning, on an empty stomach, and between meals. This pain may be relieved by using antacids, but not always. Accompanying symptoms can include hiccups, upset stomach, indigestion, vomiting and no appetite for days (Ref #2).

A diagnosis of an H. Pylori infection may take a long time, as doctors tend to omit these specific tests or assume that an ulcer is responsible for the overgrowth of the bacteria.                       

Monolaurin and H. Pylori Bacteria

Monolaurin is a medium chain fatty acid that can be extracted from coconut oil and has been shown to possess antibacterial properties (Ref #3). According to some laboratory studies, Monolaurin may kill H. Pylori bacteria, and in turn may be an effective treatment for gastritis.

Monolaurin displays a strong anti-bacterial behavior against H. pylori as compared to other chemicals. One study (Ref #4) showed that Monolaurin was the most effective of the fatty acids and monoglycerides tested in the killing of H. Pylori. Furthermore, the results were not impacted by pH, suggesting that Monolaurin might work in the hard acidity of the stomach.

A further study (Ref #5) shows that H. pylori is rapidly inactivated by medium-chain monoglycerides and lauric acid (Monolaurin) and exhibits a relatively low frequency of spontaneous development of resistance to the bactericidal activity of Monlaurin. Monolaurin was shown to be bactericidal agsint H. Pylori bacteria in as little as 15 minutes at neutral or acidic pHs.

Monolaurin does not appear to harm any useful gut bacteria. A research study of 2004 conducted in the Georgetown University Medical Centre of Washington DC revealed that Monolaurin could be very useful in treating infections as it is a safe compound that can be combined with other antibiotics as well (Ref #6). Since then, it has been used as an active ingredient in some anti-bacterial medicines. It is used to treat some common diseases like cold and swine flu.


In recent years, monolaurin has been studied for treating microorganisms, fungi, and bacteria that pose a threat to health. Research has indicated the potential of Monolaurin as an antibacterial agent as it has the power to inactivate bacteria in the laboratory. Like all dietary supplements, Monolaurin should be considered and administered under the supervision of a healthcare professional.  



  1. Kusters JG, van Vliet AHM, Kuipers EJ. Pathogenesis of Helicobacter pylori Infection. Clinical Microbiology Reviews. 2006;19(3):449-490. doi:10.1128/CMR.00054-05.

  2. IQWiG (Institute for Quality and Efficiency in Health Care) June 28, 2018 Accessed at

  3. Bergsson G, Steingrímsson O, Thormar H. Bactericidal effects of fatty acids and monoglycerides on Helicobacter pylori. Int J Antimicrob Agents. 2002 Oct;20(4):258-62.

  4. Sun CQ, O'Connor CJ, Roberton AM. Antibacterial actions of fatty acids and monoglycerides against Helicobacter pylori. FEMS Immunol Med Microbiol. 2003 May 15;36(1-2):9-17.

  5. Petschow BW, Batema RP, Ford LL. Susceptibility of Helicobacter pylori to bactericidal properties of medium-chain monoglycerides and free fatty acids. Antimicrob Agents Chemother. 1996 Feb;40(2):302-6.

  6. Preuss HG, Echard B. Enig M. Brook I, Elliott TB. Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteria. Molecular and Cellular Biochemistry April 2005, Volume 272, Issue 1–2, pp 29–34

The Role of Monolaurin in the Treatment of Bacterial Infections

Last Updated: December 14, 2018 | First Published: June 11, 2018
Reviewed by: Dr. Ahmed Zayed, M.D.

There have been many laboratory studies on the Monolaurin and bacteria

There have been many laboratory studies on the Monolaurin and bacteria

Bacterial infections are relatively common today. While the use of antibiotics has been an effective approach to the treatment of these infections for many years, modern-day healthcare systems are recognizing the increased prevalence of antibiotic resistance. One study [Ref #1] explains that the widespread resistance against antibiotic drugs is caused by the misuse and the overuse of antibiotics. Untreated bacterial infections, even in the case of antibiotic resistance, can lead to fatal complications.

Different types of bacterial infections have been identified in human patients [Ref #2]. These infections can often be classified as primary or secondary, as well as either acute or chronic. A bacterial infection can also be localized, pyogenic or generalized. Infections can affect different parts of the body, including the lungs, the throat, the gums, stomach, and other areas.

Monolaurin In The Treatment Of Infection

The human body is a host to billions of microorganisms, including bacteria. While many of these organisms are beneficial for the human body, some of them can be pathogenic, which means they cause harm. The infestation of pathogenic bacteria species in the human body can lead to the development of an infection.
This calls for the scientists to start looking at alternative options for the treatment of bacterial infections. Many natural treatments have been suggested for the use against the presence of an infection caused by bacterium species in the human body, but only a few of these substances hold clinically significant data behind their effectiveness. Monolaurin is one particular substance that has been proven effective.

Monolaurin is a naturally-derived medium chain fatty acid that can be extracted from glycerin and lauric acid [Red#3]. The substance is also a coconut fat byproduct. While this substance has become quite popular in the preservation of food, recent studies have started to take a look at the use of Monolaurin in bacterial infections.

Numerous scientific studies have been conducted and proven the effectiveness of Monolaurin in the treatment of infections caused by specific types of bacterium species.

  • Straphylococcus Aureus – This bacteria can cause skin infections, pneumonia, endocarditis, sepsis, meningitis, osteomyelitis, and more. The species have also been associated with toxic shock syndrome. One study [Ref #4] found the extracts of Monolaurin from coconut oil, combined with an agent known as lactic acid, very effective in the treatment of bacterial infections caused by the Staphylococcus aureus species. The study explains that Monolaurin resulted in a loss of membranes and cytoplasm in Staphylococcus aureus bacteria cells.

  • Enteroccocus – A group of bacterium species that often causes wound infections, as well as infections in soft tissue within the human body. One study [Ref #5] found the use of Monolaurin extracts to be statistically significant when the effects of this extract were tested on Staphylococcus aureus, Enterobacter spp, Enterococcus spp, E. vulneris, and Streptococcus spp. All of the tests performed in these studies were performed on samples obtained from skin infections.

  • Escherichia Coli – Often referred to as E. coli, when pathogenic, these bacteria can cause infections to develop in the intestines, leading to gastrointestinal discomfort, pain and other accompanying symptoms. Studies have proven Monolaurin concentrations of 20mg/ml to be effective in reducing colony growth density in human subjects.


Infections caused by bacteria can cause life-threatening complications. Antibiotics are the conventional treatment option used to eliminate the presence of a bacterial infection, but with an increased prevalence of antibiotic resistance, the world is looking for alternative methods to help treat these infections. Monolaurin has the potential to assist with the elimination of infections caused by particular types of bacterium species.

Lean more about the bacterium Monolaurin has been researched to treat on the Research page


  1. C. L. Ventola. The Antibiotic Resistance Crisis. Journal of Pharmacy and Therapeutics. April 2015.

  2. J.W. Peterson. Bacterial Pathogenesis. Medical Microbiology. 4th edition.

  3. J. Seladi-Schulman. What Is Monolaurin? Healthline. 22 August 2017.

  4. P. Tangwatcharin, P. Khopaibool. Activity of virgin coconut oil, lauric acid or monolaurin in combination with lactic acid against Staphylococcus aureus. U.S. National Library of Medicine. July 2012.

  5. B.G. Carpo, V.M. Verallo-Rowell, J. Kabara. Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from sin infections: an in vitro study. U.S. National Library of Medicine. October 2007.

Doctor, author and fitness enthusiast, Ahmed Zayed, MD, is a surgery resident with a passion for helping people live a happy healthy life. Dr. Zayed is a contributing author for Natural Cure Labs.


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