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Monolaurin and Herpes – The Definitive Guide

Last Updated: February 19, 2019 | First Published: September 2, 2018
Reviewed by: Dr. Rosmy Barrios, M.D.

Introduction to Herpes

Herpes is a common and global virus. According to the World Health Organization, an estimated 67% of the world’s population has HSV-1 (oral herpes which can cause cold sores) and 11% of the population has HSV-2 (genital herpes) [Ref #] It is possible to have a Herpes Simplex infection and not have any symptoms. Herpes is a lifelong disease and can be spread even when symptoms are not present. Antiviral medications like acyclovir can help relieve the frequency and intensity of symptoms, but there is no “cure”.


Types of Herpes

Herpesviridae is a family of DNA viruses, which include many types and strains but the most common include HSV-1, HSV-2, and Herpes Zoster.

Herpes Simplex 1 (HSV 1) – Oral Herpes

Herpes Simplex 1, or HSV-1, is most commonly known as “oral herpes”. HSV-1 can cause cold sores or fever blisters around the lips and mouth, but can also affect others parts of the body including the genital area. Johns Hopkins Medicine estimates that up to 80% of individuals in the United States has HSV-1, making it one of the most common infections. [Ref #2]

More Information: Explore additional details about Monolaurin and its potential impact on cold sores on the Insights blog.

Herpes Simplex 2 (HSV 2) – Genital Herpes

Herpes Simplex 2, or HSV-2, causes genital herpes and is almost exclusively sexually transmitted. HSV-2 effects more women than men globally, and affects upwards of 15% of people in the Americas. HSV-2 can be asymptomatic or have very mild symptoms, meaning many people can be infected without knowing it. Generally, HSV-2 causes blisters or ulcers in the genital and anal region.

More Information: Read more about HSV-2 and Monolaurin on the Insights blog.  

Herpes Zoster – Shingles

Herpes Zoster is a type of herpes virus which can cause shingles via the reactivation of the varicella zoster virus (the virus which causes chicken pox). Shingles, also known as Herpes Zoster, can cause painful skin rashes and blisters.

More Information: Read more about Herpes Zoster (Shingles) on the Insights blog 


Herpes Symptoms

Depending on the type of herpes infection, the symptoms may vary. In short:

Herpes Symptoms by Type

HSV-1 (Oral herpes)

Characterized by painful blisters on or around the lips which can be accompanied by tingling, itching, leading eventually oozing and or crusting.

HSV-2 (Genital herpes)

Similar to the symptoms of HSV-1, genital herpes can be characterized by painful blisters or sores, tingling, and or itching around the genital area.

Herpes Zoster (Shingles)

Characterized by a painful skin rash with blisters which occurs in a strip on either side of the body or face. There may also be tingling or local pain in the area before an outbreak.

Herpes Outbreak

An outbreak is simply the expression of symptoms resulting from a herpes virus infection. An initial outbreak may last days or weeks. There may be delays between outbreaks lasting weeks or months. Outbreaks and outbreak symptoms may diminish over time, and it is possible to be infected with a herpes family virus with little or no symptoms.


Traditional herpes treatments use antivirals to suppress the virus, but what if Monolaurin could actually kill the herpes virus?

Traditional herpes treatments use antivirals to suppress the virus, but what if Monolaurin could actually kill the herpes virus?

Herpes Cure

Herpes Simplex 1 and Herpes Simplex 2 are lifelong infections with no known cure. Monolaurin, a natural supplement derived from coconut, has been studied in various in vitro laboratory experiments to inactivate the Herpes Simplex virus, but this may not correlate to the inactivation of herpes virus in vivo. This section explores and highlights some academic and scientific research which may suggest Monolaurin kills herpes, however additional research is required to conclude that Monolaurin can cure herpes.

Suppressive Treatment for Herpes with Antivirals:

Controlling the frequency, duration, and intensity of herpes outbreaks is the main goal of suppression therapies and antiviral drugs. Reducing virus replication and in turn reducing the risk of transmission is another goal of antiviral therapy. Acyclovir, famciclovir, and valacyclovir are common antivirals used to treat herpes, but there is growing concern that the virus may develop resistance to the drug making them less effective [Ref #3]. Furthermore, some individuals face unwanted side effects from  antiviral pharmaceuticals including rash, hair loss, headaches, depression, nausea, diarrhea, or vomiting (Ref #15, 16, 17)

Potentially Kill Herpes by Disintegrating the Viral Envelope:

A possible alternative to suppressing the symptoms and replication of the virus may be to kill the herpes virus. Herpes is an enveloped virus, meaning there is a fatty protective layer (envelope) surrounding the virus. Monolaurin has been shown in some laboratory studies to kill enveloped viruses, which may include herpes virus.

The antiviral action, attributed to monolaurin (the monoglyceride of lauric acid), is that of solubilizing the lipids and phospholipids in the envelope of the pathogenic organisms causing the disintegration of their outer membrane. There is also evidence that medium chain fatty acids interfere with the organism’s signal transduction and the antimicrobial effect in viruses is due to interference with virus assembly and viral maturation.” [Ref #4]

"Antiviral fatty acids were found to affect the viral envelope, causing leakage and at higher concentrations, a complete disintegration of the envelope and the viral particles. They also caused disintegration of the plasma membranes of tissue culture cells resulting in cell lysis and death."[Ref #5]

Lipids commonly found in natural products could possibly be used as antiviral agents against enveloped viruses." [Ref #6]

Killing the viral envelope of the herpes virus might produce effects similar to traditional antiviral suppressant drugs without the risk of side effects or drug resistance common to pharmaceuticals. 

More Information: To learn more about enveloped viruses and Monolaurin, please see the Insights Article called Fighting Enveloped RNA and DNA Viruses


Monolaurin, made from coconut, has been shown in laboratory studies to inactivate enveloped viruses like Herpes

Monolaurin, made from coconut, has been shown in laboratory studies to inactivate enveloped viruses like Herpes

Monolaurin for Herpes – Does Monolaurin Kill Herpes?

Monolaurin has been the subject of numerous clinical studies which test if Monolaurin kills herpes, if Monolaurin is effective for herpes, and if Monolaurin can eradicate herpes. While the majority of the tests are in vitro (in the lab) and not clinically supported, the results are provocative with regard to Monolaurin’s ability to kill herpes.

Some studies and publications report success with Monolaurin to kill herpes in the lab:

"In studies performed at the Respiratory Virology Branch, Centers for Disease Control, Atlanta, Georgia, Monolaurin was found effective against 14 human RNA and DNA enveloped viruses in cell culture. These included influenza, RSV, Rubeola, Newcastle's, Coronavirus, Herpes Simplex types 1 & 2, Epstein-Barr Virus (EBV) and cytomegalovirus. Monolaurin removed all measurable infectivity by disintegrating the virus envelope." [Ref #7]

We have shown that a variety of fatty acids and fatty acid derivatives have potent antiviral effects against the lipid-containing bacteriophages PM2, ø6, and PR4 and against at least one enveloped mammalian virus, herpes simplex virus type 2.” [Ref #8]

"Unsaturated monoglycerides and alcohols of chain lengths of 16 or 18 carbons were found to be extremely potent inactivators of two enveloped viruses, herpes simplex virus type 2 and bacteriophage phi6 " [Ref 9]

These publications suggest that Monolaurin kills herpes in the lab. However, more research is needed to establish if Monolaurin cures herpes in the body.

More Information: Read more about Herpes family viruses and Monolaurin in the Insights Blog post by Dr. Zayed here.  


Monolaurin may be taken during a herpes outbreak to reduce severity and duration, and in-between outbreaks to limit frequency.

Monolaurin may be taken during a herpes outbreak to reduce severity and duration, and in-between outbreaks to limit frequency.

Monolaurin Dosage and Protocol for Herpes

Monolaurin is generally regarded as safe (GRAS) by the Food and Drug Administration [Ref #10], and some choose to take it as a dietary supplement with the goal of using Monolaurin against herpes.

A Monolaurin dosage for herpes will generally be separated into three areas, as explained below. 
For more detailed dosing information, see the Monolaurin Dosage Guide.

1. Build Up

People respond differently to dietary supplements, so it’s recommended to start slow and build up to a level you are individually comfortable with. In some cases, the strong antimicrobial properties of Monolaurin may trigger a reaction called the Herxheimer (Herx) Reaction, or “die off”. A Herx Reaction may occur if Monolaurin is taken at high doses in a short period of time, causing a die-off of more viruses and bacteria than your body can effectively filter. This may trigger an inflammatory response ironically similar to the flu, called the “Herx Reaction”. To avoid this, you may want to start with a low dose of monolaurin and slowly build up to a therapeutic dose over time.

More Information: To learn more about the causes and symptoms of the Herx Reaction / Die off, please see the Insights article : Monolaurin Die Off Symptoms.

2. During Outbreaks

During a herpes outbreak, many increase their dose of Monolaurin in response to the increased viral load. The monolaurin dosage during a herpes outbreak will depend on the individuals’ physical characteristics (weight, etc) and the severity of the symptoms. It may be best to increase monolaurin intake at the very beginning of symptoms to try and stop an outbreak before it becomes an issue. Some people will find taking 2-3 600mg capsules 3 times per day helpful during a herpes outbreak.

3. Maintenance

In-between outbreaks, some people find it beneficial to maintain a daily dose of Monolaurin to promote general health and prevent future outbreaks. A routine dose might include 1-2 capsules 2 or 3 times per day.

More Information: For more detailed information on monolaurin herpes protocols and dosing guidance, including monolaurin during a herpes outbreak, please see the Monolaurin Dosing Guide.


Monolaurin Side Effects

As mentioned in the Build Up section above, the most common symptoms individuals may encounter is a “Herx Reaction” which may be attributed to the rapid die off of virus and bacteria caused by Monolaurin. To avoid this, a slow introduction of Monolaurin at low doses might help.

Other side effects are those similar to an increased intake of coconut oil. The medium chain triglycerides found in coconut oil have been linked to side-effects like stomach discomfort, irritability, vomiting, diarrhea, and intestinal gas. [Ref #11]

More Information: Additional details on the health benefits and potential side effects of coconut oil is available in the blog post on Coconut Oil.


Monolaurin may work in conjunction with L-Lysine to reduce symptoms and duration of a Herpes infection.

Monolaurin may work in conjunction with L-Lysine to reduce symptoms and duration of a Herpes infection.

Monolaurin and L-Lysine

Monolaurin is not the only supplement which has shown promising results in laboratory studies against herpes. When combined with L-lysine, synergistic benefits may be realized.

L-Lysine has been shown to potentially reduce the symptoms and duration of a herpes infection [Ref #12]. L-Lysine has also demonstrated the potential to reduce the recurrence of herpes outbreak [Ref #13]. Yet another study showed L-lysine could help with reducing the replication of the virus in the lab [Ref #14]. These studies suggest that while Monolauin may help disable or destroy the Herpes virus, L-Lysine can play a potential accompanying role in reducing the symptoms, duration, recurrence, and replication of the herpes virus.

More Information: For additional information on L-Lysine and Monolaurin for herpes, check out the article: Monolaurin and L-Lysine – Better Together.

More Information: Lean more about 16 additional helpful supplements which have been studied for their antiviral properties on the Immune Support page.


Additional Information and Help

There is a lot of information available to those looking to learn more about monolaurin and herpes. When researching monolaurin and herpes, be mindful of personal opinion and always look for appropriate scientific references and citations. 

NCBI (PubMed)

NCBI is a free online database of over 28 million citations for biomedical literature from MEDLINE, life science journals, and online books. The United States National Library of Medicine (NLM) maintains the database, which is a great way of getting direct access to many of the studies cited on this website.

Herpes Forums

Forums and support groups are a good way to find peer-to-peer support. There are also secret groups on various social media sites (like Facebook) to meet others with similar questions and concerns. It is highly recommended to get involved in your local sexual heath communities - the empathy and support they provide is genuine and many find it helpful.

More Cited Research

The Research Page of this site contains a list of curated studies featuring Monolaurin and herpes studies, all containing original NCBI or DOI links for further reading and fact-checking. 


Ready to Try Monolaurin, but Not Sure Where to Start?

There are many factors which should be considered when purchasing Monolaurin, which include:

  • What Monolaurin source is best - Coconut or Palm Kernel

  • What is the recommended way to take Monolaurin - Capsule or Pellet

  • What is an Excipient, and why does it matter - Synthetic or Natural

  • What hat to look for to ensure manufacturing safety - Certifications and Location

All of these questions can be answered in the comprehensive Monolaurin Buying Guide


References:

  1. World Health Organization, 31 January 2017, http://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus

  2. Oral Herpes. (n.d.). Retrieved from Johns Hopkins Medicine: https://www.hopkinsmedicine.org/healthlibrary/conditions/adult/infectious_diseases/Oral_Herpes_22,OralHerpes

  3. Frobert E, Ooka T, Cortay JC, et al. Resistance of Herpes simplex virus type 1 to acyclovir: Thymidine kinase gene mutagenesis study. Antiviral Res 2006 Aug 30

  4. Arora R, Chawla R, Marwah R, Arora P, Sharma RK, Kaushik V, Goel R, Kaur A, Silambarasan M, Tripathi RP, Bharwaj JR. Potential of Complementary and Alternative Medicine in Preventive Management of NovelH1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. Evidence-Based Complementary and Alternative Medicine Volume 2011 (2011), Article ID 586506, 16 pages

  5. Thormar H, Isaacs CE, Brown HR, Barshatzky MR, Pessolano T. Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides.AntimicrobialAgents and Chemotherapy. 1987 Jan;31(1):27-31.

  6. Thormar H, Isaacs CE, Kim KS, Brown HR. Inactivation of visna virus and other enveloped viruses by free fatty acids and monoglycerides. Annals of the New York Academy of Science. 1994 June 6, 724:465–471.

  7. Hierholzer JC and Kabara JJ. In vitro effects of Monolaurin compounds on enveloped RNA and DNA viruses. Journal of Food Safety 4:1, 1982

  8. Kabara JJ. The Pharmacological Effect of Lipids. Champaign, Ill, USA: American Oil Chemist’s Society; 1978. Page 92

  9. Sands J, Auperin D, Snipes W. Extreme sensitivity of enveloped viruses, including Herpes Simplex, to long chain unsaturated monoglycerides and alcohols. Antimicrobial Agents and Chemotherapy. 15; 1:67-73, 1979.

  10. FDA : 21CFR184.1505 ; https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1505

  11. Nakatsuji, T., Kao, M. C., Fang, J.-Y., Zouboulis, C. C., Zhang, L., Gallo, R. L., & Huang, C.-M. (2009). Antimicrobial Property of Lauric Acid Against Propionibacterium acnes: Its Therapeutic Potential for Inflammatory Acne Vulgaris. The Journal of Investigative Dermatology, 129(10), 2480–2488. http://doi.org/10.1038/jid.2009.93

  12. Griffith R.S.,Norins A.L., Kagan C. A Multicentered Study of Lysine Therapy in Herpes simplex Infection. Dermatologica 1978;156:257–267

  13. Griffith R.S., Walsh D.E., Myrmel K.H., Thompson R.W., Behforooz A. Success of L-Lysine Therapy in Frequently Recurrent Herpes simplex Infection. Dermatologica 1987;175:183–190

  14. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. 1980;60(1):85-7.

  15. Everyday Health Acyclovir (Zovirax) Side Effects http://www.everydayhealth.com/drugs/acyclovir

  16. Web MD, Drugs & Medications Valtrex http://www.webmd.com/drugs/2/drug-14126/valtrex-oral/details#side-effects

  17. Sharma A, Mohan K, Sharma R, Nirankari VS. Alopecia following oral acyclovir for the treatment of herpes simplex keratitis. Middle East Afr J Ophthalmol. 2014 Jan-Mar;21(1):95-7. doi: 10.4103/0974-9233.124131.

Monolaurin and L-Lysine – Better Together

Last Updated: January 8, 2019 | First Published: August 13, 2018
Reviewed by: Dr. Razak Nohri, Pharm.D, M.Phil, MBA

Working together, L-lysine may reduce the symptoms and duration of an HSV outbreak while Monolaurin may work to destroy the virus reducing recurrence.

Working together, L-lysine may reduce the symptoms and duration of an HSV outbreak while Monolaurin may work to destroy the virus reducing recurrence.

Lysine and Monolaurin may play a role in clearing, containing, or preventing viral infections such as Herpes Simplex Virus (HSV). Lysine is a natural amino acid, which the body cannot produce on its own. L-lysine must be obtained from food sources or through medically approved supplements containing the amino acid.

Monolaurin is formed in the body when food containing glycerine and lauric acid is consumed. It is unknown exactly how much the body converts, making supplementation necessary for therapeutic quantities. 

L-Lysine: Promising Research in the treatment of HSV

In one study (Ref #1, 2), control groups were given L-lysine monohydrochloride daily to study the effects of lysine on the rate of recurrence on Herpes Simplex Virus (HSV). The study reported that L-lysine is extremely effective in slowing down the occurrence of HSV infections, reducing symptoms, and healing time was significantly reduced.

In another study (Ref # 3), a randomized, double-blind, placebo-controlled, cross-over study of forty-one patients it was found that oral ingestion of L-Lysine monohydrochloride shows evidence of decreasing the recurrence rate of herpes simplex attacks in nonimmunocompromised hosts. L-Lysine may be capable of decreasing the severity of symptoms associated with HSV recurrences.

A third study (Ref #4) showed L-lysine has an inhibitory effect on the multiplication of herpes simplex virus in cell cultures. The study included 65 patients in a double-blind, placebo-controlled, crossover study. In the study, significantly more patients were recurrence-free during lysine than during placebo treatment, suggesting that certain patients may benefit from prophylactic lysine administration.

Effects Of L-Lysine and Monolaurin on HSV

L-lysine and Monolaurin have shown the ability to slow the occurrences of the Herpes Simplex Virus (Type 1 and Type 2) in laboratory studies, and may produce positive results when combined.

L-lysine for reducing symptoms and duration of an HSV Infection 

L-lysine may help to reduce the occurrence of HSV breakouts. As noted in the research above, l-lysine has been shown in some laboratory studies to help reduce the severity and duration of HSV breakouts.

Monolaurin for disabling the HSV virus

Monolaurin has been shown to assist with disabling the HSV virus, as detailed in previous Insights articles. This can help prevent the virus from reproducing, and may decrease the risk of transmission. Additionally, monolaurin has also been shown to dissolve the HSV virus in some laboratory studies suggesting Monolaurin may be able to kill HSV. 

When combining L-lysine and Monolaurin, the results can be advantageous. While L-lysine may slow the occurrence of HSV symptoms and duration of breakouts, Monolaurin may dissolve the virus and eventually kill the virus over time.

References

  1. Griffith R.S.,Norins A.L., Kagan C. A Multicentered Study of Lysine Therapy in Herpes simplex Infection. Dermatologica 1978;156:257–267 https://doi.org/10.1159/000250926

  2. Griffith R.S., Walsh D.E., Myrmel K.H., Thompson R.W., Behforooz A. Success of L-Lysine Therapy in Frequently Recurrent Herpes simplex Infection. Dermatologica 1987;175:183–190 https://doi.org/10.1159/000248823

  3. McCune MA , Perry HO , Muller SA , O'Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis. 1984 Oct;34(4):366-73. https://www.ncbi.nlm.nih.gov/pubmed/6435961 \

  4. Milman N, Scheibel J, Jessen O. Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlled crossover study. Acta Derm Venereol. 1980;60(1):85-7. https://www.ncbi.nlm.nih.gov/pubmed/6153847

Treat Herpes naturally and effectively with Monolaurin

Last Updated: December 2, 2018 | First Published: September 22, 2015
Reviewed by: Dr. Jennifer Meza, M.D.

Could Monolaurin go beyond traditional suppressive techniques and actually destroy the virus?

Could Monolaurin go beyond traditional suppressive techniques and actually destroy the virus?

A common goal for controlling a herpes infection is finding a therapy to help manage symptoms and outbreaks. There are suppressive methods of reducing symptoms which include antivirals and creams, but they only treat the symptoms - not the underlying cause.

In this article, we will explore how Monolaurin is a natural and effective therapy for the treatment and management of herpes which may kill the virus instead of simply suppressing it.

Traditional Antiviral (suppressive) Treatment:

There are several antiviral drugs on the market which may help reduce the frequency, duration or severity of herpes outbreaks by supressing viral activity. However, these pharmaceuticals often come at a great financial expense and with serious side effects and allergic reactions including rash, hair loss, headaches, depression, nausea, diarrhea, or vomiting [Ref #1, 2, 10]. If taken for a long duration, the herpes virus may even develop resistance to the antiviral drugs rendering them less effective [Ref #3]. Antivirals traditionally work by inhibiting the DNA replication of the virus, slowing the spread of the virus.

Natural Treatment using Monolaurin to kill Herpes:

Herpes is a DNA virus which belongs to the family Herpesviridae which include Varicella (chicken pox), Zoster (shingles), Epstein–Barr (mono), and Herpes Simplex Virus (cold sores and genital herpes). These viruses are "enveloped", which means the virus has a lipid or fatty capsule around the DNA which enables the virus to have a chronic impact on the nervous system. Once infected with a herpes virus, the virus can stay dormant in the nervous system and erupt when the immune system is weakened.

Monolaurin may Kill Herpes Virus:

Monolaurin is able to break down the fatty envelope which protects the herpes virus, killing the virus and also inhibiting the replication of the virus.  Numerous laboratory tests have validated this.

“The antiviral action, attributed to monolaurin (the monoglyceride of lauric acid), is that of solubilizing the lipids and phospholipids in the envelope of the pathogenic organisms causing the disintegration of their outer membrane. There is also evidence that medium chain fatty acids interfere with the organism’s signal transduction [Ref #7] and the antimicrobial effect in viruses is due to interference with virus assembly and viral maturation [Ref #8].”[Ref #6]

A further study goes to demonstrate:

"In studies performed at the Respiratory Virology Branch, Centers for Disease Control, Atlanta, Georgia, Monolaurin was found effective against 14 human RNA and DNA enveloped viruses in cell culture. These included influenza, RSV, Rubeola, Newcastle's, Coronavirus, Herpes Simplex types 1 & 2, Epstein-Barr Virus (EBV) and cytomegalovirus. Monolaurin removed all measurable infectivity by disintegrating the virus envelope."[Ref #9]

Laboratory research has shown Monolaurin is able to inactivate and kill multiple variants of the herpes virus including Herpes simplex virus-1, Herpes simplex virus-2, and Herpes viridae (all) [4, 5].

We have shown that a variety of fatty acids and fatty acid derivatives have potent antiviral effects against the lipid-containing bacteriophages PM2, ø6, and PR4 and against at least one enveloped mammalian virus, herpes simplex virus type 2.” [Ref #7]

Monolaurin's antiviral properties may not just stop the virus from replicating, but also kill the active virus by breaking the outer membrane of the virus.

Preventing Outbreaks using a "Maintenance" Dose of Monolaurin:

Herpes can remain dormant in your body for years, and outbreaks can be triggered through stress or a weakened immune system. It is important to have a line of defense to stop these outbreaks before they happen.

As the Herpes virus DNA leaves the host cell to move to another cell, Monolaurin may help stop the transfer and kill the virus in the act. Maintaining a constant presence of Monolaurin in your system may help prevent the replication and spread of the herpes virus in the body. A daily regimen of Monolaurin, even at low doses, may help suppress outbreaks before they happen.

Monolaurin Treatment Options:

It is important that the treatment approach reflects the severity and stage of the infection. There are two principal Monolaurin dosage considerations for Herpes: 1.) New Symptoms & Outbreaks, and 2.) Ongoing Maintenance, which may include an introductory build-up period. 

Example Monolaurin Dosage Table for an average adult:

# Capsules x Per day Duration
Introductory Build-up 1 building to 3 1 building to 3 2 weeks
New Symptoms & Outbreaks 2-3 capsules 3 times per day 6 weeks
Maintenance & Ongoing Health 1-2 Capsules 1-3 times per day Ongoing

For more detailed dosing information, please visit the Monolaurin Dosing page

Note: Herxheimer (Herx) Reaction or viral "die off" :

Natural Cure Labs Monolaurin contains premium and pure monolaurin, which may have strong anti-viral effects. For some patients, it may require a slow buildup to avoid producing a "die off" symptom called the "Herxheimer Reaction". The Herxheimer Reaction occurs when bacteria, viruses, fungi, begin to die off and release their endotoxins and lipoproteins into the body faster than they can be removed. It can cause a sickness that is ironically similar to the flu, including body aches, headaches and sluggishness. This feeling is temporary and can be avoided by a slow introduction of monolaurin into your daily dietary supplement routine. It is recommended taking 1 or 2 capsules per day for the first three days, slowly increasing the dosage to up to 3 capsules three times per day over the course of two weeks.

1.) For New Symptoms & Outbreaks:

Natural Care Labs Monolaurin can be taken in large doses for aggressive outbreaks. A recommended treatment for a new herpes infection or outbreak is 2 or 3 capsules up to three times per day for six weeks or until the flare-ups are no longer common.

2.) For Maintenance and Ongoing Health:

Once symptoms have subsided, it is important to maintain overall health and prevent future outbreaks. A recommended maintenance routine includes 1 or 2 capsules of Natural Cure Labs Monolaurin up to three times per day.

If this is your first time taking Monolaurin, be sure to note some of the important considerations when selecting your first Monolaurin product in the Buying Guide

All therapies, both natural and pharmaceutical, should be administered under the guidance and supervision of a health care professional.

Looking to Try Monolaurin, but Not Sure Where to Start?

There are many factors which should be considered when choosing a Monolaurin brand, which include:

  • What Monolaurin source is best - Coconut or Palm Kernel

  • What is the recommended way to take Monolaurin - Capsule or Pellet

  • What is an Excipient, and why does it matter - Synthetic or Natural

  • What hat to look for to ensure manufacturing safety - Certifications and Location

All of these questions can be answered in the comprehensive Monolaurin Buying Guide

Learn more:

If you’re interested in learning more about Monolaurin and Herpes, check out the post “Monolaurin and Herpes – The Definitive Guide” which explores the difference between HSV-1, HSV-2, and Herpes Zoster, details herpes symptoms, and explores the science and literature behind many herpes treatment options.

As with any nutritional supplement or medicine, it should be administered and monitored by a healthcare professional. 

References:

  1. Everyday Health Acyclovir (Zovirax) Side Effects http://www.everydayhealth.com/drugs/acyclovir

  2. Web MD, Drugs & Medications Valtrex http://www.webmd.com/drugs/2/drug-14126/valtrex-oral/details#side-effects

  3. Frobert E, Ooka T, Cortay JC, et al. Resistance of Herpes simplex virus type 1 to acyclovir: Thymidine kinase gene mutagenesis study. Antiviral Res 2006 Aug 30

  4. Enig M. Lauric oils as antimicrobial agents: Theory of effect, scientific rationale, and dietary application as adjunct nutritional support for HIV infected individuals. In: Watson R, ed. Nutrients and Foods in AIDS. Boca Raton, FL: CRC Press, 1998.

  5. Lieberman S, Enig MG, Preuss HG. A Review of Monolaurin and Lauric Acid Natural Virucidal and Bactericidal Agents. Alternative & Complimentary Therapies, December 2006.

  6. Arora R, Chawla R, Marwah R, Arora P, Sharma RK, Kaushik V, Goel R, Kaur A, Silambarasan M, Tripathi RP, Bharwaj JR. Potential of Complementary and Alternative Medicine in Preventive Management of NovelH1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. Evidence-Based Complementary and Alternative Medicine Volume 2011 (2011), Article ID 586506, 16 pages http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957173/

  7. Kabara JJ. The Pharmacological Effect of Lipids. Champaign, Ill, USA: American Oil Chemist’s Society; 1978. Page 92

  8. Projan SJ, Brown-Skrobot S, Schlievert PM, Vandenesch F, Novick RP, J Bacteriol. Glycerol monolaurate inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction. 1994 Jul; 176(14):4204-9

  9. Hierholzer JC and Kabara JJ. In vitro effects of Monolaurin compounds on enveloped RNA and DNA viruses. Journal of Food Safety 4:1, 1982

  10. Sharma A, Mohan K, Sharma R, Nirankari VS. Alopecia following oral acyclovir for the treatment of herpes simplex keratitis. Middle East Afr J Ophthalmol. 2014 Jan-Mar;21(1):95-7. doi: 10.4103/0974-9233.124131.

Herpes Family Viruses and Monolaurin

Last Updated: December 15, 2018 | First Published: June 28, 2018
Reviewed by: Dr. Ahmed Zayed, M.D.

Herpes affects a huge part of the population. Could Monolaurin help alleviate the virus?

Herpes affects a huge part of the population. Could Monolaurin help alleviate the virus?

Herpes simplex viruses affect a huge part of the population. The World Health Organization estimates that at least three billion people have herpes (Ref #1) type 1 while around 400 million have herpes type 2.  Here are the herpes symptoms (Ref #2) that you need to look out for:

  • Herpes Type 1 or HSV1. Cold sores appear in the mouth and lips.

  • Herpes Type 2 or HSV2. This type of herpes simplex virus causes genital herpes. There is inflammation in the genital area which may itch or burn. Blisters also appear near the genitals.

HSV1 and HSV2 are usually transmitted through the oral or genital contact. But there is one form of herpes that you can contract in another way: herpes zoster or shingles. You can contract herpes zoster through the respiratory tract and via direct contact with the blisters.

Herpes is a chronic disease which unfortunately has no cure (Ref #3). Common medications used to treat herpes are antivirals like Denavir, Zovirax, and Famvir. These antivirals work by inhibiting the symptoms of the herpes simplex virus. Antivirals, however, can cause various side effects like recurring headaches, dizziness, nausea, and stomach pains.

Treatment of Herpes Using Monolaurin

Monolaurin is one of the newest organic compounds that researchers are looking into tapping to treat herpes. Since it is a naturally occurring chemical compound, the risks of complications are lesser compared to current medications. It is also more beneficial for patients who are immunosuppressed. Monolaurin combats herpes simplex and herpes zoster viruses by:

  • Disintegrating viral membranes (Ref #4). Monolaurin's antiviral capabilities stop viruses from enveloping its hosts. This process, in turn, causes protective viral cell membranes to disintegrate.

  • Destabilizing the viral layer. Monolaurin incorporates itself in the structure of viruses halting any replication.

  • Inhibiting growth and toxin production. For genital herpes, scientists are exploring its capability of stopping growth and protecting the host cell membrane. Monolaurin as a topical treatment may work to prevent sexual transmission (Ref #5). When monolaurin is inserted into the hydrogel, its antiviral properties inactivate most sexually transmitted viruses.

  • Weakening the fat-coating of viruses. Herpes viruses are known to integrate themselves with the body’s fat layer which can help explain their chronic nature. Monolaurin strips herpes’s fat coating making them susceptible against monolaurin’s anti-viral capabilities.

Conclusion

A lot of research is still being undertaken in the future uses of Monolaurin in treating and possibly curing herpes viruses. In the meantime, some doctors have prescribed Monolaurin as supplements. Considering it is FDA-approved and has no known side effects, it is definitely worth a try.

References                                                                                                   

  1. “Globally, an Estimated Two-Thirds of the Population under 50 Are Infected with Herpes Simplex Virus Type 1.” World Health Organization, World Health Organization, www.who.int/news-room/detail/28-10-2015-globally-an-estimated-two-thirds-of-the-population-under-50-are-infected-with-herpes-simplex-virus-type-1.

  2. “Herpes Simplex: Herpes Type 1 and 2.” WebMD, WebMD, www.webmd.com/genital-herpes/pain-management-herpes#1.

  3. Ayoade, Folusakin O. “Herpes Simplex: Background, Microbiology, Pathophysiology.” Background, Pathophysiology, Etiology, 6 Apr. 2018, emedicine.medscape.com/article/218580-overview. https://emedicine.medscape.com/article/218580-overview

  4. Thormar, H et al. “Inactivation of Enveloped Viruses and Killing of Cells by Fatty Acids and Monoglycerides.” Antimicrobial Agents and Chemotherapy 31.1 (1987): 27–31. Print.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC174645/

  5. Schlievert, Patrick M. et al. “Glycerol Monolaurate Does Not Alter Rhesus Macaque (Macaca Mulatta) Vaginal Lactobacilli and Is Safe for Chronic Use .” Antimicrobial Agents and Chemotherapy 52.12 (2008): 4448–4454. PMC. Web. 17 June 2018.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592867/

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